Doctors don’t know precisely what causes Lupus. They think genetics, hormones, and your environment may be involved.
Scientists haven’t yet discovered a gene that causes Lupus. They have discovered that it tends to run in certain families. If you have a family member with Lupus, you are between 5 and 13 percent more likely to get Lupus, according to some.
Certain ethnic groups share common genes that may make them more likely to get Lupus. Your chances of getting the disease are higher if you are: African-American, Asian, Hispanic/Latino, Native American, Native Hawaiian, or Pacific Islander.
Doctors think that Estrogen, a hormone, may have something to do with Lupus. Men and Women have Estrogen in their bodies, but Women have much more, which may have something to do with why women tend to get Lupus more often than men.
Some women with Lupus also get symptom flare-ups around their period or during pregnancy when Estrogen levels are higher. But this doesn’t prove that Estrogen causes Lupus.